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2012/2013

Acute changes in glycemic homeostasis in response to brief high-intensity intermittent exercise in obese adults

Journal of Exercise Science & Fitness, 2012, 10(2): 97-100

Author(s)Jinlei Nie
Zhaowei Kong
Julien S. Baker Tom K. Tong
Seng Hong Lei
Qingde Shi
Summary

This study investigated the acute changes in glycemic homeostasis in response to brief, high-intensity, intermittent exercise in obese adults. Ten obese adults (age: 25.3 ± 5.1 years; body mass index: 32.0 ± 4.0) volunteered to participate in the study. The time-course changes in blood glucose in response to a 75-g oral glucose tolerance test were examined following: high-intensity intermittent exercise (HIE) of four 30-second all-out cycling efforts interspersed with 4-minute active recovery periods; 24 hours of recovery post-HIE (REC); and no treatment (control, CON). Blood glucose in each trial was measured before, and 30, 60, 90, and 120 minutes after glucose intake (GI). Blood glucose (mmol/L) at 30 minutes post-GI in the HIE (6.9 ± 0.4) trial was significantly lower (p < 0.05) than the corresponding values of the CON (9.0 ± 0.4) and REC (8.8 ± 0.4) trials. Blood glucose concentration at 120 minutes post-GI in the REC (5.7 ± 0.3) trial was also significantly lower (p < 0.05) than the corresponding value of the CON (6.9 ± 0.4) trial. When blood glucose values were plotted against corresponding time points, the area under the curve (mmol/L/minute) of the CON (890 ± 43) trial was significantly greater (p < 0.05) than that of the HIE (834 ± 40) and REC (846 ± 32) trials. The HIE and REC conditions were not significantly different (p > 0.05). This study demonstrated the improvement in glycemic homeostasis in obese adults immediately after brief, high-intensity, intermittent exercise. These effects were maintained for at least 24 hours postexercise. The findings may be useful in the development of time-efficient lifestyle intervention strategies for improving obesity-related risk factors for diabetes.


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